The main aim of projects conducted in The Laboratory of Molecular Biology and Preclinical Research is to evaluate biological activities of newly designed and synthesized chemical compounds.
Close collaboration with Medicinal Chemistry Unit results in smooth and fast transition from the idea of a new drug to the evaluation of its potential therapeutic efficacy.
Hits from in vitro screens are further assessed in the complete battery of in vivo tests including toxicity and proof of concept evaluations.
Biologists, biotechnologists and pharmacists working in this team are also involved in search for a new potential drug targets. Their expertise allows them to use the latest methods of molecular and cell biology and to fully exploit modern laboratory equipment. In vitro cell culture (including primary neuronal cultures), real-time PCR, Western-blotting, immunohisto- and cytochemistry are examples of the routinely used techniques. Such a broad range of methods is required to cover wide and diversified research areas, which are explored by five different research teams: Metabolic Group, Neurodegeneration Group, Oncology Group, siRNA Group, Protein Analysis Group.
Medicinal Chemistry Unit
Drug Product Development Unit
Biologists, biotechnologists and pharmacists working in this team are also involved in search for a new potential drug targets. Their expertise allows them to use the latest methods of molecular and cell biology and to fully exploit modern laboratory equipment. In vitro cell culture (including primary neuronal cultures), real-time PCR, Western-blotting, immunohisto- and cytochemistry are examples of the routinely used techniques. Such a broad range of methods is required to cover wide and diversified research areas, which are explored by five different research teams: Metabolic Group, Neurodegeneration Group, Oncology Group, siRNA Group, Protein Analysis Group.
Medicinal Chemistry UnitDrug Product Development Unit
Celon Pharma Ltd
ul. Ogrodowa 2A
05-092 Lomianki, Kielpin
ul. Ogrodowa 2A
05-092 Lomianki, Kielpin
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